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Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance
서명 / 저자 Integrated cardiac safety : assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / J. Rick Turner, Todd A. Durham.
저자명 Turner, J. Rick.
Durham, Todd A.
발행사항 Hoboken, N.J. : John Wiley & Sons, c2009.

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00054403

소장위치 / 청구기호

6층 과학·기술자료실 / RC677 T87 2009

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청구기호 RC677 T87 2009
형태사항 xxviii, 470 p. : ill. ; 25 cm.
언어 English
서지주기 Includes bibliographical references (p. 397-455) and index.
내용 The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety.
주제 Cardiovascular toxicology.
Heart --Effect of drugs on.
Drugs --Side effects --Testing.
Drugs --Safety measures.
Cardiovascular Diseases --prevention & control.
Drug Design.
Medication Errors.
Product Surveillance, Postmarketing --methods.
Safety Management --methods.
LCCN 2008022807
ISBN 9780470229644 (cloth) , 0470229640 (cloth)
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